Absorbed dose estimates at the cellular level for 111In
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Date
2006
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Publisher
Azerbaijan National Academy of Sciences Institute of Radiation Problems ve Turkish Atomic Energy Authority
Abstract
Microdosimetric calculations of Auger and conversion electrons of 111In have been evaluated for single cell and cell clusters. A VsBasic program has been used to calculate stopping power, LET, range values and deposited energies per decay for Auger and conversion electrons of 111In. Chemical composition of cell has been taken into account in this model and results were compared with water medium. Besides, total absorbed doses have been calculated for the radionuclides distributed randomly within the cell and clusters. Cross-fire irradiation has been considered for clusters of cells. In this case, absorbed doses per cell within a cluster were found significantly higher than absorbed doses per single cell depending on the cluster size. Results were concluded that 111In is a promising radionuclide for therapy of micrometatases which their width is mm or smaller.
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Keywords
Absorbed dose estimates, Absorbe edilen doz, Internal conversion electrons, Dahili dönüşüm elektronları, Auger electrons, Burgu elektronları, Cell, Hücre, Microdosimetry, 111In
Citation
Ünak, P. (2006). Absorbed dose estimates at the cellular level for 111In. The Fourth Eurasian Conference on Nuclear Science and Its Application : Presentations, (s. 449-453). 31 October-3 November 2006. Baku, Azerbaijan.