Syntheses based on cholanic acid, ∆ 23 - cholone and 23 - amino norcholane
Loading...
Files
Date
1967-04
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
T.A.E.C. Çekmece Nuclear Research Center
Abstract
Reduction of cholanic acid (III) with lithium aluminum hydride gave cholanyl alconol (IV). Benzoate, chloride,
pyridinium chloride hydrate, ethyl carbonate, S-metnyl xanthate derivatives of cholanyl alcohol have been prepared, ∆23-Cholene has been obtained by the pyrolysis of the last two products. Osmium tetroxide hydroxylation of ∆-cnolene afforded 23,24-dioxy cholane (VIII). Schmid reaction on cholanic acid gave 23-amino norcholane (IX). Acetyl, benzoyl, and tosyl derivatives of the amine have been prepared. Reaction with potassium isocyanate gave norcholanyl urea (IX e). Norcholanic acid (X) has been obtained by the alcaline permanganate oxidation of 23-amino norcholane. Lithium aluminum hydride reduction of norcholanic acid gave norcholanyl alconol (XI).
Description
TENMAK D.N.. 8121
Keywords
Organic chemistry, Organik kimya, Delta 23
Citation
Ünseren, E. (1967). Syntheses based on cholanic acid, ∆ 23 - cholone and 23 - amino norcholane. İstanbul : T.A.E.C. Çekmece Nuclear Research Center.