Preparing 99mTc labeled magnetite nanoparticles as drug carriers

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dc.contributor.authorMedine, E. İ.
dc.contributor.authorÜnak, Perihan
dc.contributor.authorID162664tr_TR
dc.contributor.departmentBölüm Yoktr_TR
dc.date.accessioned2019-02-19T12:38:16Z
dc.date.available2019-02-19T12:38:16Z
dc.date.issued2006
dc.description.abstractDextran coated 99mTc labeled magnetite nanoparticles were prepared in this study. Magnetite was synthesized by a coprecipitation reaction that occurs upon mixing 0.37 g FeCl3, 1.51 g FeCl24H20 with dextran T-40 (50w%, 10 ml, MW 40000). NH4OH solution (7.5% w/v) was added up to pH 10. A black magnetite precipitate was formed. Prepared magnetite nanoparticles were labeled using with 74 MBq 99mTcO4 after adding 100 µi (1 mg/ml) freshly prepared SnCl2 solution. Precipitated magnetic carrier particles were centrifuged and washed with pure water until the rinses became neutral. Labeling yield was over 96% and radiochemical purity was approximately 98%. The average size of particles was 150.2±6.1 nm.tr_TR
dc.identifier.citationMedine, E. İ. ve Ünak, P. (2006). Preparing 99mTc labeled magnetite nanoparticles as drug carriers. The Fourth Eurasian Conference on Nuclear Science and Its Application : Presentations, (s. 537-538). 31 October-3 November 2006. Baku, Azerbaijan.tr_TR
dc.identifier.endpage538tr_TR
dc.identifier.startpage537tr_TR
dc.identifier.urihttp://kurumsalarsiv.tenmak.gov.tr/handle/20.500.12878/1127
dc.language.isoengtr_TR
dc.publisherAzerbaijan National Academy of Sciences Institute of Radiation Problems ve Turkish Atomic Energy Authoritytr_TR
dc.relation.journalThe Fourth Eurasian Conference on Nuclear Science and Its Application : Presentations, 31 October-3 November 2006. Baku, Azerbaijan.tr_TR
dc.rightsinfo:eu-repo/semantics/openAccesstr_TR
dc.subject99mTc
dc.subjectTc-99m / Technetium-99mtr_TR
dc.subjectTeknesyum-99mtr_TR
dc.subjectPreparing magnetite nanoparticlestr_TR
dc.subjectManyetit nanopartikülleri hazırlamatr_TR
dc.subjectDrug carrierstr_TR
dc.subjectİlaç taşıyıcılartr_TR
dc.titlePreparing 99mTc labeled magnetite nanoparticles as drug carrierstr_TR
dc.typeconferenceObjecttr_TR
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IV. Eurasian conference on nuclear science and its application : presentations, 31 October- 3 November 2006. Baku, Azerbaijan.