Browsing IV. Eurasian conference on nuclear science and its application : presentations, 31 October- 3 November 2006. Baku, Azerbaijan. by All Authors "162664"
(Azerbaijan National Academy of Sciences Institute of Radiation Problems ve Turkish Atomic Energy Authority, 2006) Medine, E. İ.; Ünak, Perihan; 162664; Bölüm Yok
Dextran coated 99mTc labeled magnetite nanoparticles were prepared in this study. Magnetite was synthesized by a coprecipitation reaction that occurs upon mixing 0.37 g FeCl3, 1.51 g FeCl24H20 with dextran T-40 (50w%, 10 ml, MW 40000). NH4OH solution (7.5% w/v) was added up to pH 10. A black magnetite precipitate was formed. Prepared magnetite nanoparticles were labeled using with 74 MBq 99mTcO4 after adding 100 µi (1 mg/ml) freshly prepared SnCl2 solution. Precipitated magnetic carrier particles were centrifuged and washed with pure water until the rinses became neutral. Labeling yield was over 96% and radiochemical purity was approximately 98%. The average size of particles was 150.2±6.1 nm.